Cellular Matrix Natural HA
SERVICE
The Art of Timeless Rejuvenation
A revolutionary innovation in skin care, combining two treatment concepts in one for natural results. This treatment is Cellular Matrix Natural HA enriched by your Platelets Growth Factors and the combination of Regen PRP and HA provides better contouring and seems to accelerate cellular regeneration, making this combination the right tool for skin hydration.
Cellular Matrix Natural HA Enriched by Your Platelets’ Growth Factors
Cellular Matrix BCT-HA
Cellular Matrix tubes allow the preparation of autologous platelet-rich plasma (RegenPRP) combined with a non-crosslinked hyaluronic acid (HA) in a closed-circuit system.
Cellular Matrix® technology combines the complementary clinical effects of RegenPRP® and hyaluronic acid (HA), giving better and longer-lasting results in clients with osteoarthritis.
The resulting Cellular Matrix RegenPRP-HA preparation is named CM-PRP-HA.
Hyaluronic Acid
Hyaluronic acid is a key molecule involved in skin moisture and has a unique property in retaining water.
More than 25 years of clinical experience in skin hydration and volume correction.
Major component of the extracellular matrix.
Binds water and creates volume.
Stimulates migration and proliferation of cells.
Hyaluronic acid seems to improve the activity of several molecules contained in platelet-rich plasma.
Both PRP and HA have been extensively used to improve lubrication, modulate inflammation and modify the joint catabolic micro-environment, aiming not only to reduce clinical symptoms, but also to slow down OA progression2.
When PRP and HA are used in combination these effects are enhanced and prolonged. HA creates a bioactive scaffolding in which the platelets progressively release their growth factors. RegenPRP does not negatively affect the mechanical, elastic or viscous properties of HA1.
As demonstrated by Smith et al., fibrin polymerization in the presence of HA generates a clot with large pores, which facilitates cell migration.
Cellular Matrix is a unique, regulatory-approved, patented technology, that allows the safe, closed-circuit preparation of a cell-friendly PRP-HA network in which platelets and plasma components are retained.
CM-PRP-HA has an excellent safety profile in clinical practice.
Technology platform for standardized autologous regenerative medicine
The simple, safe, and efficient point-of-care preparation of autologous platelet-rich plasma.
- User-independent standardized preparation
- Minimum volume of blood required
- Safe closed-circuit system
- Mechanical isolation of PRP using a biologically inert gel after a 5-minute centrifugation
- Reversible anticoagulation with a pharmaceutical grade solution of sodium citrate at pH 7
- Minimal learning curve and ease of use
- Operationally and clinically efficient process
- Facilitates and streamlines routine practice
- Certified technology for the preparation of RegenPRP® combined with hyaluronic acid (HA) (CM-PRP-HA)
- Contains 2 ml of non-crosslinked HA at a concentration of 20 mg/ml (40 mg total)
- HA is produced by bacterial fermentation, thus free of animal proteins
- Demonstrated safety and efficacy
- Evidence-based outcomes for numerous therapeutic indications
- Large number of clinical studies, with over 200 publications
- RegenPRP® is standardized, leucocyte reduced, and easily reproducible
- Regen Lab-specific separating gel technology guarantees minimal variability
- Platelets recovery in CM-PRP-HA >70%
- High platelet quality
- Viable & functional platelets
- Full plasma recovery
- No loss of plasma growth factors and fibrinogen
- Leucocyte reduced PRP Depletion ~ 94.3% of pro-inflammatory granulocytes, leaving mainly lymphocytes and monocytes
- Virtually no red blood cells
- Depletion of ~ 99.5% of erythrocytes
Clinical Evidence
Significant improvement in skin elasticity.
Facial Appearance
In a prospective study, 31 clients were treated by mesotherapy with the PegenPRP and HA combination prepared with Cellular Matrix (CM-PRP-HA) at 0, 1, and 2 months. Clinical benefits were evaluated by FACE-Q scores and biophysical measurements of skin elasticity.
Comparison of FACE-Q scores showed significant improvement at 6 months compared with baseline (p=0.03). Similarly, objective biophysical measurements showed significant improvement in skin elasticity (R5) compared to baseline (p+0.036) at 6 months post-treatment.
No serious side effects were reported.
Skin Quality
A prospective study with 5 clients evaluated the clinical benefits of the combination of RegenPRP and HA prepared with Cellular Matrix (CM-PRP-HA) when used as a mesotherapy on the hand face. Evaluations of skin quality and tonus were performed by both the treated subjects and evaluators.
A significant improvement was observed in the skin of the hands and face of all subjects, including improvement in skin quality and tonus, as well as wrinkle depth after three treatment sessions.
Cellular Matrix improves skin tonus and quality.
Cellular Regeneration
CM-PRP-HA can be used either as a stand-alone treatment injected directly into the superficial dermis or together with a deeper injection into the superficial musculoaponeurotic system (SMAS).
HA acts as a bio-scaffold, increasing the growth factor residence time in tissue and enhancing cell migration and regeneration. CM-PRP-HA makes the balancing of volume and lifts much easier and gives an instant result.
The combination of RegenPRP and HA provides better contouring and seems to accelerate cellular regeneration, making this combination the right tool for skin hydration.
Intended use of the device
The device is used to prepare a combination of hyaluronic acid (HA) and platelet-rich plasma (PRP) for intra-articular injection into the knee for symptomatic treatment of articular pain and improvement of joint mobility.
Why Clients Choose Healthy Skin
Your Invitation
The Reverse Mesotherapy Ritual supports your skin in five key dimensions:
Please feel free to contact us for a booking, or may also connect with us on our WHATSAPP MOBILE No. +66 89 866 2545 Healthy Skin & Beauty Treatment Center.
